Dr. Lillian Royal and Dr. Melissa Smith graduated together from North Carolina State University College of Veterinary Medicine in 2006. They are now the proud owners of Wilkes Veterinary Hospital. Dr. Royal focuses primarily on small animal medicine and exotic animal medicine. Dr. Melissa focuses on equine and large animal medicine as well as small and large animal surgery.

Dr. Audie Bloise is Wilkes Veterinary Hospital's part-time and emergency surgeon.